CHEMISTRY 20L

Introductory Organic Chemistry Laboratory

Fall 2008

 

Instructor: Dr. Cynthia Kellen-Yuen

 

Contact Info:   office:  SQU 424 A           e-mail:   ckyuen@csus.edu              phone:  278-5348

                                                                                                                   

Office Hours         Dr. Kellen-Yuen:  M: 1-2;  W,F: 9-10  or by appointment

 

Faculty website:  www.csus.edu/indiv/k/kellen-yuenc/          WebCT site:  https://online.csus.edu   

 

Texts                     Chemistry 20L Laboratory Manual

                              Organic Laboratory Techniques, 3rd ed., Fessenden, Fessenden and Feist

 

Required               Bound, lined laboratory-grade notebook (preferably with page numbers),

Materials              calculator, gloves and chemistry-grade laboratory goggles.

                              A laboratory coat is highly recommended.

 

Prerequisites        Successful completion of or concurrent enrollment in Chem 20

 

Course Description: Basic organic experimental techniques.  Experimental topics include:  melting points, purification of solids, distillation, gas chromatography, extraction, and functional group qualitative analysis.  Specifically designed for Biological Sciences majors and others who want to meet the Chemistry minor requirements for a lower division organic laboratory. 

 

Learning Objectives:  Students will learn basic organic laboratory techniques, which will be utilized to prepare, separate, purify and identify organic compounds.  Students will also learn some instrumental techniques (e.g. gas chromatography and/or infrared spectroscopy).  Students will also be required to keep a laboratory-grade notebook, to explain their laboratory findings in writing, to perform basic calculations related to the lab, and to familiarize themselves with safety information sources.

 

Student Responsibilities:  Before starting any lab work, a student must familiarize him/herself with lab procedures, chemicals, equipment, hazards, safety procedures, and disposal procedures associated with the work being performed.  If the instructor feels that a student is unprepared the student will be asked to leave.  There are no make-up labs or make-up quizzes without prior approval by the instructor.  Students are required to properly clean their work area before leaving lab or their grade will be lowered.

 

Attire:  Students will always come to the lab in clothing appropriate to a chemistry lab.  This means long sleeves, long pants and shoes that cover the foot.  This is the best way to protect yourself in the case of a chemical spill.  A lab coat or lab apron is a wise investment since it also protects your clothing.  STUDENTS WILL WEAR CHEMICAL-GRADE LABORATORY GOGGLES AT ALL TIMES IN THE LABORATORY.  THERE ARE NO EXCEPTIONS.  Any student who must be repeatedly warned to put on his/her goggles will be told to leave the class.  Contact lenses should never be worn in a chemistry laboratory.

 

Attendance:  This lab meets only once a week.  Thus, if you miss one lab period, you have missed one week of class!  Attendance will be taken every lab period.  You are allowed one unexcused absence; two or more will result in a failing grade in the class.

Experiments: The experiments to be performed this semester are listed below along with the basic time-line for the semester.  These experiments and or the timing of the experiments may change depending upon the needs of the class.  Check for the up-dated schedule on WebCT during the course of the semester.

 

Date

Experiment/Activity

Reading in Text

9/8

Intro, Check-in, and lectures

P. 1-22

9/15

Melting Points (15 pts)

P.39-48

9/22

TLC of Analgesics (15 pts)

P. 133-140

9/29

Isolation of Analgesics (15 pts)

P. 119-132

10/6

Catch-up and lectures

 

10/13

Quiz #1, Nitration (15 pts)

P. 153-159, 23-38

10/20

Nitration continues

 

10/27

SN1/SN2 analysis (15 pts)

 

11/3

Qualitative Analysis of Alcohols and Alkenes (15 pts)

 

11/10

Quiz #2, Oxidation (15 pts)

P. 163-178

11/17

Microwave Aspirin synthesis (15 pts)

P. 23-38

11/24

Carvone (15 pts)

P. 77-92, 107-110

12/1

Quiz #3, Carvone continues--spectroscopy

P. 163-178

12/8

Clean-up and check-out

 

 

Final Exam—Friday Dec. 19, 8-10 am

 

 

Grading:  Your grade for the course will be based on your experiment points, quizzes and final exam, your laboratory notebook, and your laboratory technique throughout the course of the semester (see below for instructions on keeping a laboratory notebook).

 

Experimental points

135

Lab book and technique

50

Quizzes (3)

75

Final

100

Total

      360 pts.

                                                                         

Letter grades are assigned based on a range of: A to A- = 90.0% and above,  B+ to B- = 89.9-80.0%,  C+ to C- = 79.9-70.0%,  D = 69.9-60.0%,  F = below 60.0%

 

Cheating and Plagiarism:  Plagiarism and cheating are strictly forbidden and will result in a ZERO GRADE.  This includes submission of any work which is not your own, falsification of lab data, use of old laboratory reports (yours or someone else’s), copying from another student's report (yes, even lab partners must have their own unique answers), reporting data for an experiment you did not perform, using extra materials during testing, programming data into a calculator, having other people take tests for you, altering exams after they have been graded, etc.  While it is acceptable for your initial data numbers to be the same as your partner’s, we expect each student to be capable of thinking for him/herself.  As such, identical answers (in word or structure of calculation problems) will be considered evidence of cheating.

 

Cleanliness in Lab:  Due to problems encountered in previous classes, students are warned that they are directly held responsible for the cleanliness of the lab, since messy labs pose hazards to the students and add costs to the department in terms of clean-up time and wasted chemicals.  Therefore the instructor can fine every student in the class up to 5 points per day if the laboratory room is found to be messy or unsafe.  Students are encouraged to remind each other to clean up their areas to avoid losing points.  If any student notices that one of their lab mates is not following the rules, they should report this to the lab instructor immediately.  Students will be required to ensure that the lab room is clean before leaving for the day. 

 

Laboratory Notebook: Read text pp. 8-22.  The correct notebook for the lab is a hardcover, bound notebook containing lined pages.  A loose-leaf or spiral notebook is not satisfactory because pages are easily removed and lost.  If the pages are not numbered, number them before using the book.  Make sure you write your name, address, and telephone number on the inside cover, in case it is lost.  Record your locker number and combination of your locker in your lab book or in some convenient place.  Leave two pages at the front of the lab book for a table of contents.  Then enter your experiments consecutively.  All data will be recorded in permanent ink as it is collected.  NEVER ERASE IN A NOTEBOOK.  If an error is made, ONE line is drawn through the mistake.  DO NOT SCRATCH OUT ERRORS AND DO NOT RIP OUT PAGES FROM THE LAB BOOK.  Points will be deducted for illegible notebooks, however we do understand that the only "perfect" lab book is one that has been copied.  Make sure your work is neat and easily followed.

 

The lab book will include:

Ø      A table of contents (with page references)

Ø      A Hazard Table listing the name and structure of each chemical used in the lab, its melting or boiling point, and any important toxicity data (including and LD50) or other hazards  Note: this data can be found in “Hazardous Properties of Industrial Materials” edited by Sax or in any standard list of Material Safety Data Sheets (MSDSs).  Both can be found in the 5th floor Service Center; the Sax book is in the reference section on the 3rd floor of the Library; and MSDS information can be found on-line (for example from Sigma-Aldrich or Fisher)

Ø      Each experiment should have its own page on which a title, date, and a brief outline of the experimental steps are written,

Ø      Amounts of chemicals used in a reaction, modifications to the original lab procedure, results, observations, and conclusions should be written in for every experiment performed

 

Laboratory Reports: Each experiment written in the lab manual includes a lab report form.  You are NOT to record data directly onto the lab report form—it goes into the lab notebook.  The data from the notebook is then used to complete the lab report  form (this ensures that you lab report form is neat and that you always have a copy of the data in case anything should happen to your lab report form). Graphs, spectra, or other papers that might be generated in the lab should be attached to the completed lab report form for submission to instructor.

 

Lab Reports are due the week after the experiment is completed, at the BEGINNING of the lab period.  Late reports lose 10% of the grade for every day the are late.  Lab reports are NOT accepted after the graded reports have been returned to the class.

 

THE INSTRUCTOR’S INITIALS must be on the current lab report form before you leave the lab each day.  Lab reports which are NOT initialed by the instructor will NOT be accepted for grading.  It is the student’s responsibility to make sure the lab report is initialed before leaving the lab for the day.