The Impact of Aging on Endogenous Cardiovascular Progenitor Cells
in Human Neonates and Adults
Mary Kearns-Jonker, Ph.D.
Associate Professor of Medicine
Loma Linda University School of Medicine
Tuesday, April 22nd
6:00 - 7:00 pm
University Union, Ballroom Room 1
The Sacramento State STEM Scholars Lecture Series welcomes Mary Kearns-Jonker, Associate Professor of Medicine at Loma Linda University School of Medicine. Her talk titled “The Impact of Aging on Endogenous Cardiovascular Progenitor Cells in Human Neonates and Adults” will address her current research focused on cardiovascular progenitor cells.
Cardiovascular progenitor stem cell-based treatment has the potential to improve functional outcome in patients with heart failure. Dr. Kearns-Jonker’s research team is studying a promising new population of cardiovascular progenitor cells (CPC) that can be isolated as clonal populations from the heart of human neonates and adults. These CPC’s are capable of regeneration when administered for stem-cell based repair. They can be differentiated into all cardiovascular lineages, including cardiac myocytes, endothelial cells, and smooth muscle cells. The molecular basis for enhanced regenerative capacity unique to the neonatal CPC is being utilized in their laboratory to develop novel approaches to improve the functional outcome of cell-based treatment for the heart.
Dr. Kearns-Jonker earned her Ph.D. in Anatomy at McGill University, Montreal, Canada in 1985. Prior to her current position as an Associate Professor of Medicine in the Department of Pathology and Human Anatomy at Loma Linda School of Medicine in Loma Linda, CA, she has held positions at NIH, Cedars-Sinai Medical Center and the University of Southern California. She is an expert in transplantation immunology and develops novel approaches using stem cells for myocardial repair. She has authored over 40 peer-reviewed research articles and received numerous awards including the Career Enhancement Award for Stem Cell Research from NIH in 2008 and the GCAT Award from Loma Linda University School of Medicine in 2012.
|Regenerative Medicine Lecture Series
Dr. Rosalee Carter
Office phone: (916) 278-7391
STEM Scholars Series
Coordinator, Center for STEM Excellence