Contact Information
Name: Erin E. Olsan
Title: Assistant Professor
Office Location: TSC 4005
Email: e.olsan@csus.edu
Office Phone: 916.278.4069
Mailing Address: 6000 J Street, Sacramento, CA 95819
Office Hours: Mon 1:30 -3:00pm (F21)
Research Projects/Interests
My main research interests include host-microbiota interactions that define and limit the composition and abundance of members of the microbiota. My current projects investigate 1) nitrate respiration in anoxic or hypoxic environments using the bacteria Klebsiella oxytoca and 2) nectar inhabiting microbes from Aquilegia spp.
Publications
Cevallos, S. A., Lee, J. Y., Velazquez, E. M., Foegeding, N. J., Shelton, C. D., Tiffany, C. R., Parry, B. H., Stull-Lane, A. R., Olsan, E. E., Savage, H. P., Nguyen, H., Ghanaat, S. S., Byndloss, A. J., Agu, I. O., Tsolis, R. M., Byndloss, M. X., & Bäumler, A. J. (2021). 5-Aminosalicylic Acid Ameliorates Colitis and Checks Dysbiotic Escherichia coli Expansion by Activating PPAR-γ Signaling in the Intestinal Epithelium. mBio, 12(1), e03227-20. https://doi.org/10.1128/mBio.03227-20
Lee, J. Y., Cevallos, S. A., Byndloss, M. X., Tiffany, C. R., Olsan, E. E., Butler, B. P., Young, B. M., Rogers, A., Nguyen, H., Kim, K., Choi, S. W., Bae, E., Lee, J. H., Min, U. G., Lee, D. C., & Bäumler, A. J. (2020). High-Fat Diet and Antibiotics Cooperatively Impair Mitochondrial Bioenergetics to Trigger Dysbiosis that Exacerbates Pre-inflammatory Bowel Disease. Cell host & microbe, 28(2), 273–284.e6. https://doi.org/10.1016/j.chom.2020.06.001
Olsan, E. E., West, J. D., Torres, J. A., Doerr, N., & Weimbs, T. (2018). Identification of targets of IL-13 and STAT6 signaling in polycystic kidney disease. American journal of physiology. Renal physiology, 315(1), F86–F96. https://doi.org/10.1152/ajprenal.00346.2017
Bronner, D. N., Faber, F., Olsan, E. E., Byndloss, M. X., Sayed, N. A., Xu, G., Yoo, W., Kim, D., Ryu, S., Lebrilla, C. B., & Bäumler, A. J. (2018). Genetic Ablation of Butyrate Utilization Attenuates Gastrointestinal Salmonella Disease. Cell host & microbe, 23(2), 266–273.e4. https://doi.org/10.1016/j.chom.2018.01.004
Byndloss, M. X., Olsan, E. E., Rivera-Chávez, F., Tiffany, C. R., Cevallos, S. A., Lokken, K. L., Torres, T. P., Byndloss, A. J., Faber, F., Gao, Y., Litvak, Y., Lopez, C. A., Xu, G., Napoli, E., Giulivi, C., Tsolis, R. M., Revzin, A., Lebrilla, C. B., & Bäumler, A. J. (2017). Microbiota-activated PPAR-γ signaling inhibits dysbiotic Enterobacteriaceae expansion. Science (New York, N.Y.), 357(6351), 570–575. https://doi.org/10.1126/science.aam9949
Olsan, E. E., Byndloss, M. X., Faber, F., Rivera-Chávez, F., Tsolis, R. M., & Bäumler, A. J. (2017). Colonization resistance: The deconvolution of a complex trait. The Journal of biological chemistry, 292(21), 8577–8581. https://doi.org/10.1074/jbc.R116.752295
Rivera-Chávez, F., Zhang, L. F., Faber, F., Lopez, C. A., Byndloss, M. X., Olsan, E. E., Xu, G., Velazquez, E. M., Lebrilla, C. B., Winter, S. E., & Bäumler, A. J. (2016). Depletion of Butyrate-Producing Clostridia from the Gut Microbiota Drives an Aerobic Luminal Expansion of Salmonella. Cell host & microbe, 19(4), 443–454. https://doi.org/10.1016/j.chom.2016.03.004
Olsan, E. E., Matsushita, T., Rezaei, M., & Weimbs, T. (2015). Exploitation of the Polymeric Immunoglobulin Receptor for Antibody Targeting to Renal Cyst Lumens in Polycystic Kidney Disease. The Journal of biological chemistry, 290(25), 15679–15686. https://doi.org/10.1074/jbc.M114.607929
Weimbs, T., Olsan, E. E., & Talbot, J. J. (2013). Regulation of STATs by polycystin-1 and their role in polycystic kidney disease. JAK-STAT, 2(2), e23650. https://doi.org/10.4161/jkst.23650
Olsan, E. E., Mukherjee, S., Wulkersdorfer, B., Shillingford, J. M., Giovannone, A. J., Todorov, G., Song, X., Pei, Y., & Weimbs, T. (2011). Signal transducer and activator of transcription-6 (STAT6) inhibition suppresses renal cyst growth in polycystic kidney disease. Proceedings of the National Academy of Sciences of the United States of America, 108(44), 18067–18072. https://doi.org/10.1073/pnas.1111966108
Courses That I Teach
BIO 184: General Genetics
BIO 221A: Cell and Molecular Methods and Techniques
BIO 222: Molecular Biology
Professional Associations
American Society for Microbiology (https://asm.org/)